ImmuneWatch DETECT
TCR specificity annotations for comprehensive T-cell response analysis.
Struggling with finding the epitope-specificity of your T-cell receptors?
ImmuneWatch’s DETECT platform uses machine learning to annotate the epitope specificity of T-cell receptor (TCR) sequences.
"Together with ImmuneWatch we were able to assess vaccine-induced T-cell signatures in our unique longitudinal sample collection of cancer patients. Based on antibody titers, it has previously been shown that cancer patients induce a weaker response towards COVID19 vaccines. T-cell immunity in this context is far less characterized and understood. Thanks to the ImmuneWatch DETECT platform we were able to take a deep dive into the SARS-CoV-2-specific T-cell response of our cancer patient cohort. "
ImmuneWatch DETECT wins Machine Learning competition
We are excited to share our recent win in the IMMREP23 Kaggle competition focused on TCR (T-cell receptor) specificity prediction.
Read the article
Our offering
Make your vaccine design process more data-driven by implementing machine learning and approaches from reverse vaccinology.
Reverse vaccinology as a service
TCR Sequencing Whitepaper
TCR sequencing for cancer vaccine development
To know the efficacy of your cancer vaccine, it is crucial to analyse the T cell response. Because of its versatility, TCR sequencing is a rising tool to monitor such immune responses. However, the full potential of TCR sequencing remains unrealised at present.
This white paper is directed toward researchers and developers of therapeutic cancer vaccines. It offers a brief overview of TCR sequencing and how it has been applied in the field of therapeutic cancer vaccination. Additionally, we highlight common challenges encountered in the data analysis and present examples of how these can be overcome with state-of-the-art data analysis techniques.
Our offering
For industry professionals we offer a tailored and feature-rich version of ImmuneWatch DETECT, designed to meet industry-specific needs. In addition, ImmuneWatch supports research and education. ImmuneWatch DETECT is therefore free to use for academics and non-profit organisations. This dual approach aims to advance both academic and professional pursuits in our field.
ImmuneWatch DETECT
ImmuneWatch DETECT as service
Generate Epitope-specific training data
ImmuneWatch DETECT
ImmuneWatch DETECT + IMWdb
FAQ
Find more information and answers to frequently asked questions on our documentation pages.
Can IMW-DETECT detect any kind of epitope?
ImmuneWatch DETECT is an algorithm that falls into the “seen epitope models” category. This means that it needs to have training data on an epitope, before it can detect TCRs related to this epitope.
IMWdb currently contains more than 1700 epitopes and is continuously expanded. In addition, we offer a service to generate the data specifically for your epitope of interest. Request a quote here.
A true “unseen epitope model” is currently being researched.
Is ImmuneWatch DETECT only limited to TCR Beta chains?
No, ImmuneWatch DETECT is able to annotate both the Alpha and Beta chains of TCRs. In addition, it can also work Delta and Gamma chains.
Do you also offer TCR sequencing?
Yes, we can help you out with your TCR sequencing project as well. Feel free to contact us for a quote for your project.
Comment HeronTrack vous aide-t-il à gérer votre équipement?
Outre la localisation de vos outils, HeronTrack vous permet de suivre et de planifier vos inspections internes et externes. HeronTrack intègre les rapports de tous les organismes d'inspection externes et propose des formulaires qui peuvent être utilisés pour les inspections internes telles que les outils électriques, les échelles et autres. En outre, les réservations d'outils et les réparations peuvent également être gérées via l'application mobile et web.
Existe-t-il différents droits d'accès dans HeronTrack?
Il y a deux groupes d'utilisateurs : ceux qui n'ont accès qu'à l'application mobile, comme les ouvriers et les conducteurs, et ceux qui ont accès à l'application mobile et à l'application web, comme les informaticiens, les responsables d'entrepôt, les chefs de projet, etc.
